Table 1.
Summary of binding constant data from six batches of AS filaments
Kd and Ki values (nM) | |||||
---|---|---|---|---|---|
Me-BTA1 | PIB | FDDNP | SB13 | BF1 | |
AS | 4.09 ± 0.82 | 16.5 ± 4.36 (4.16#) | 210.17 ± 81.38 | 87 ± 20.96 | 4.78 ± 0.43* |
Aβ | 4.2a | 25b, 4.7c | 42b | 6d | 3a |
Comparative literature values for in vitro generated Aβ fibrils are shown; # and * indicates the data from one or four batches of AS filaments respectively.