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Simplified gene configurations in the RCCX and HLA-DRB regions on MHC reference haplotypes. The COX and QBL haplotype are monomodular for RCCX, whereas the PGF, SSTO and DBB haplotypes are bimodular. Each C4 gene may encode a C4A or a C4B protein. C4L and C4S are long and short C4 genes, respectively. 21A and 21B are CYP21A ( pseudogene) and CYP21B, respectively. DRB2, DRB6, DRB7, DRB8 and DRB9 are pseudogenes.
