Table 1.
Named genes induced in 6-h TNF-α-treated chromaffin cells vs. control based on microarray analysis
| Gene | Ratio | Accession no. | GeneID |
|---|---|---|---|
| Signal transduction | |||
| Nuclear factor of κ-light chain gene enhancer in B-cells inhibitor, α | 5.69 ± 0.77 | NM_010907 | 18035 |
| Guanine nucleotide binding protein (G protein), γ5 subunit | 3.33 ± 0.04 | NM_010318 | 14707 |
| Tumor necrosis factor, α-induced protein 3 | 2.83 ± 0.32 | NM_009397 | 21929 |
| Chimerin (chimaerin) 2 | 2.15 ± 0.06 | NM_023543 | 69993 |
| Secretion | |||
| Synapsin III | 2.49 ± 0.18 | NM_013722 | 27204 |
| Immune response | |||
| Proteasome (prosome, macropain) 28 subunit, β, transcript variant 1 | 2.24 ± 0.08 | NM_011190 | 19188 |
| Proliferation/differentiation | |||
| Fibroblast growth factor 2 | 2.09 ± 0.04 | NM_008006 | 14173 |
| Unknown function | |||
| IBR domain containing 3 | 2.49 ± 0.01 | XM_991982 | 75234 |
The GenBank accession no. and the Gene cluster (GeneID) for each gene are indicated. The ratios ± sem were determined from three different experiments. The highlighted genes (in bold) correspond to TNF-α-stimulated genes in both 6- and 48-h microarray.