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Follicle development in 5-month-old wild-type (WT) and transgenic (TG) ovaries. Numbers of primary and secondary follicles were determined in wild-type and transgenic ovaries at 5 months of age. Ovaries were serially sectioned and every fifth section was counted, and total follicle numbers were determined. These data represent the mean ± sem of combined results from analysis of four mice per age and genotype (*, P ≤ 0.05).
