Table 1.
Stratus OCT™ Retinal Thickness in the Central Subfield According to Clinical Characteristics in Diabetic Subjects with Minimal or No Retinopathy
| Overall | By Gender |
|||||||
|---|---|---|---|---|---|---|---|---|
| Women | Men | |||||||
| N | Mean ± SD | P-value§ Unadjusted | P-value§ Adjusted for Gender | N | Mean ± SD | N | Mean ± SD | |
| Overall | 97 | 201 ± 22 | ||||||
| Gender | <0.001 | --- | ||||||
| Women | 48 | 194 ± 23 | ||||||
| Men | 49 | 209 ± 18 | ||||||
| Retinopathy Severity | 0.71 | 0.70 | ||||||
| Level 10 (No retinopathy) | 67 | 201 ± 21 | 38 | 196 ± 22 | 29 | 207 ± 20 | ||
| Level 20 (Very mild NPDR) | 30 | 203 ± 23 | 10 | 185 ± 27 | 20 | 211 ± 15 | ||
| Age | 0.63‡ | 0.98‡ | ||||||
| < 55 years | 49 | 202 ± 22 | 26 | 194 ± 23 | 23 | 210 ± 18 | ||
| >= 55 years | 48 | 201 ± 22 | 22 | 194 ± 23 | 26 | 207 ± 18 | ||
| Combination Diabetes Type/Duration | 0.15 | 0.11 | ||||||
| Type 1 - < 10 years | 10 | 212 ± 12 | 6 | 214 ± 11 | 4 | 210 ± 16 | ||
| Type 1 - >= 10 years | 14 | 203 ± 24 | 6 | 190 ± 20 | 8 | 212 ± 22 | ||
| Type 2 - < 10 years | 46 | 197 ± 23 | 24 | 189 ± 24 | 22 | 205 ± 19 | ||
| Type 2 - >= 10 years | 27 | 205 ± 20 | 12 | 195 ± 23 | 15 | 212 ± 14 | ||
| Duration of Diabetes | 0.14 | 0.18 | ||||||
| < 10 years | 56 | 199 ± 22 | 30 | 194 ± 24 | 26 | 205 ± 18 | ||
| >= 10 years | 41 | 204 ± 21 | 18 | 193 ± 21 | 23 | 212 ± 17 | ||
| Diabetes Type | 0.17 | 0.14 | ||||||
| Type 1 | 24 | 207 ± 20 | 12 | 202 ± 20 | 12 | 211 ± 20 | ||
| Type 2 | 73 | 200 ± 22 | 36 | 191 ± 24 | 37 | 208 ± 17 | ||
| HbA1c* | 0.37‡ | 0.23‡ | ||||||
| < 8% | 34 | 210 ± 18 | 13 | 200 ± 16 | 21 | 216 ± 17 | ||
| >= 8% | 13 | 215 ± 15 | 6 | 212 ± 14 | 7 | 218 ± 16 | ||
| Fellow Eye Retinopathy Severity † | 0.27 | 0.33 | ||||||
| Level 10 (No retinopathy) | 67 | 200 ± 22 | 34 | 193 ± 23 | 33 | 206 ± 19 | ||
| Level 20 (Very mild NPDR) | 12 | 205 ± 27 | 5 | 185 ± 29 | 7 | 219 ± 14 | ||
| Worse than level 20 | 9 | 208 ± 23 | 4 | 199 ± 30 | 5 | 214 ± 15 | ||
| Best Corrected Visual Acuity (letter score) | 0.21‡ | 0.24‡ | ||||||
| 20/12 – 20/20 (93-85) | 46 | 203 ± 20 | 20 | 197 ± 22 | 26 | 208 ± 17 | ||
| 20/20 – 20/25 (84-80) | 29 | 203 ± 22 | 18 | 198 ± 20 | 11 | 210 ± 23 | ||
| 20/25 – 20/32 (79-74) | 22 | 196 ± 26 | 10 | 179 ± 27 | 12 | 210 ± 15 | ||
| Refractive Error (Spherical Equivalent) | 0.39‡ | 0.26‡ | ||||||
| ≥ 0.00 D | 51 | 201 ± 21 | 25 | 196 ± 21 | 26 | 205 ± 19 | ||
| < 0.00 D to −3.00 D | 35 | 201 ± 24 | 18 | 189 ± 25 | 17 | 213 ± 15 | ||
| < −3.00 D | 11 | 207 ± 21 | 5 | 204 ± 24 | 6 | 210 ± 19 | ||
1 subject completed the fundus photography 11 weeks after completion of OCT
*
Not done for 50 subjects
†
Not done for 8 subjects and nongradable for 1 subject
‡
Continuous measure of characteristic used in calculation of p-value
§
P-value from least squares regression models