Table 3.
Relevant Databases in Literature: Mean + SD Retinal Thickness
| Result By Gender (CP=Center Point; CSF=Central Subfield) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reference | Machine | Population | Gender, Mean or Median Age | N | Center Point | Central Subfield | Men | Women | P-Value if available |
| Hee2 | OCT (not Stratus OCT™) | Healthy | 45% Men, Age 38 yrs | 73 Eyes (41 Subj) | 152 + 21 | 174 + 18 | CSF = 181 | CSF = 169 | P =.04 (CSF) |
| Diabetic, no DR | 75% Men, Age 55 yrs | 55 Eyes (31 Subj) | 158 + 20 | 179 + 17 | Not Available | ||||
| Lattanzio10 | OCT* | Healthy | 64% Men, Age 52 yrs | 50 Eyes (50 Subj) | 162 + 13 | Not Available | CP Not Correlated | ||
| Diabetic, no DR | Not Available | 46 Eyes (Subj # unk) | 211 + 38 | Not Available | Not Available | ||||
| Fritsche11 | RTA† | Healthy | 50% Men, Age 30 yrs | 10 Eyes (10 Subj) | Not Available | 152 + 15 | CSF = 154 | CSF = 151 | |
| Diabetic, no DR | 56% Men, Age 54 yrs | 9 Eyes (9 Subj) | Not Available | 181 + 26 | CSF = 189 | CSF = 172 | |||
| Massin3 | OCT (not Stratus OCT™) | Healthy | 40% Men, Age 46 yrs | 60 Eyes (30 Subj) | 146 + 20 | 170 + 18 | CSF = 178 CP = 153 | CSF = 165 CP = 140 | P=.0139 (CSF) |
| Diabetic, no DR | Not Available | 30 Eyes (15 Subj) | 144 + 14 | 174 + 19 | Not Available | ||||
| Wong7 | OCT2 | Healthy | 51% Men, Age 41 yrs | 117 Eyes (117 Subj) | Not Available | Not Available | CSF = 203 CP=174 | CSF = 189 CP=168 | P = .001 (CSF) |
| Paunescu8 | Stratus OCT™ | Healthy | 60% Men, Age 31 yrs | 10 Eyes (10 Subj) | Std=178+29‡ High=164+21‡ | Std=206+21‡ High=204+20‡ | Not Available | ||
| Browning6 | Stratus OCT™ | Healthy§ | Age 64 yrs | 52 Eyes (48 Subj) | Not Available | 197 + 31 | Not Available | ||
| Chan9 | Stratus OCT™ | Healthy | 30% Men, Age 43 yrs | 37 Eyes (37 Subj) | Auto=182+23¶ Manual=170+18¶ | 212 + 20 | CSF = 204 | CSF = 207 | |
| Fraser-Bell** | Stratus OCT™ | Healthy | 48% Men, Age 48 yrs | 245 Eyes (245 Subj) | 172 | 203 | CSF = 205 | CSF = 196 | P <.001 (CSF) |
| DRCR.net | Stratus OCT™ | Diabetic, no DR | 51% Men, Age 55 yrs | 97 Eyes (97 Subj) | 166 + 23 | 201 + 22 | CSF = 209 | CSF = 194 | P<.001 |
*
Not OCT 3. Center point obtained from average of three line scans through presumed foveal center.
†
Retinal Thickness Analyzer, not an OCT, evaluation of mean foveal thickness.
‡
Results using 6 mm scan (fast macular scans) and 3.5 mm scan (high density).
§
Article provided data on subjects with diabetes but not specifically subjects with diabetes and no retinopathy.
¶
Automatically generated values and values determined by manually locating the minimum value along each radial scan using the raw data and averaging over those values.
**
Fraser-Bell S, et al. IOVS 2005; ARVO E-Abstract 1542