Table 2.
Genes significantly altered in response to Bacillus anthracis infection in murine lungs at 8 hr
| GenBank ID | Gene Name | Function | FC |
|---|---|---|---|
| Up-regulated in Response to B. anthracis Infection | |||
|
| |||
| AV075715 | Clusterin (Clu) | Stress response | 2.1 |
| NM_138648 | Oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) | Inflammation; cell adhesion | 1.9 |
|
| |||
| Down-regulated in Response to B. anthracis Infection | |||
|
| |||
| U96752 | Major histocompability complex Q1b (H2-K1) | Antigen presentation | −2.5 |
| BB428671 | Platelet-derived growth factor, D polypeptide (Pdgfd) | Regulation of progression through cell cycle; proliferation | −2.1 |
| AV169310 | Surfactant associated protein C (Sftpc) | Regulation of liquid surface tension; regulatory gas exchange | −2.0 |
FC = fold-change
Negative sign (−) before fold-change value indicates down-regulation
Genes shown more than once were represented by more than one probe set on the array, and each was determined separately to be altered in response to Bacillus anthracis treatment