Table 4.
Genes significantly altered in response to Bacillus anthracis infection in murine hearts at 8 hr
| GenBank ID | Gene Name | Function | FC |
|---|---|---|---|
| Up-regulated in Response to B. anthracis Infection | |||
|
| |||
| AB006361 | Prostaglandin D synthetase (Ptgds) | Conversion of PGH2 to PGD2; smooth muscle contraction/relaxation | 1.7 |
|
| |||
| Down-regulated in Response to B. anthracis Infection | |||
|
| |||
| NM_007788 | Casein kinase II, alpha 1 polypeptide (Csnk2a1) | Wnt receptor signaling pathway | −1.8 |
| NM_011638 | Transferrin receptor (Tfrc) | Iron ion homeostasis | −1.9 |
FC = fold-change
Negative sign (−) before fold-change value indicates down-regulation
Genes shown more than once were represented by more than one probe set on the array, and each was determined separately to be altered in response to Bacillus anthracis treatment