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. 2008 May 7;6:6. doi: 10.1186/1477-3155-6-6

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Copyright © 2008 Vieira and Carmona-Ribeiro; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Amphotericin B particles covered by a thin layer of cationic lipid, at high P, and surrounded by a layer of carboxymethyl cellulose further adsorb a layer of cationic polyelectrolyte. Effect of PDDA concentration on zeta-average diameter (A) and zeta-potential (B) for AmB/DODAB BF/CMC/PDDA complexes. Final DODAB, AmB and CMC concentrations were 0.1 mM, 0.05 mM and 0.1 g.L^-1, respectively. Interactions DODAB BF/AmB and CMC took place over 20 minutes and AmB/DODAB BF/CMC and PDDA, over 30 minutes.