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. Author manuscript; available in PMC: 2008 Jun 3.
Published in final edited form as: Diabetes. 2005 Jun;54(6):1698–1705. doi: 10.2337/diabetes.54.6.1698

FIG. 1.

FIG. 1

ET-1 lowers plasma membrane PIP2 and impairs insulin action. 3T3-L1 adipocytes were exposed to 10 nmol/l ET-1 for the indicated times and left untreated (A) or treated (B) with 10 nmol/l insulin for 30 min. Representative plasma membrane PIP2 (A) and GLUT4 (B) images from three experiments are shown. IF, immunofluorescence; PM, plasma membrane.