. Author manuscript; available in PMC: 2008 Jun 3.

Published in final edited form as: J Biol Chem. 2004 Oct 8;280(9):7519–7529. doi: 10.1074/jbc.M407438200

Table IV. cPLA₂ partially regulates E. coli killing in vitro but has no effect on neutrophil-mediated E. coli phagocytosis or neutrophil FcγII/III or CD11b surface expression.

	FcγII/III surface expression	CD11b surface expression				E. coli phagocytosis by neutrophils in vitro	E. coli killing by neutrophils in vitro
	FcγII/III surface expression	Control	fMLP	PMA	OZ	E. coli phagocytosis by neutrophils in vitro	E. coli killing by neutrophils in vitro
	arbitrary units					%
PLA₂g4a(+/+)	26 ± 2	63 ± 34	136 ± 81	413 ± 196	85 ± 34	28 ± 16	59 ± 9.4
PLA₂g4a(−/−)	25 ± 2	68 ± 29	171 ± 141	353 ± 141	94 ± 38	34 ± 6	34 ± 15
n	6	5	5	5	5	5	7
p Value^a	0.18	0.94	0.63	0.55	0.63	0.49	0.005

Neutrophils from PLA₂g4a(+/+) versus PLA₂g4a(−/−) mice, paired Student’s t tests (two-tailed and unequal variance).

Table IV. cPLA2 partially regulates E. coli killing in vitro but has no effect on neutrophil-mediated E. coli phagocytosis or neutrophil FcγII/III or CD11b surface expression.