Skip to main content
. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Dev Biol. 2008 Mar 4;317(1):325–335. doi: 10.1016/j.ydbio.2008.02.029

Fig. 5. Zic2a promotes PT formation in cooperation with components of the hedgehog signaling pathway.

Fig. 5

Embryos of different genetic backgrounds were injected with a conMO (A, C, E) or a zic2aMO (B, D, F) and stained for dlx2a expression by ISH at the prim-5 stage. (A, B) Wild type embryos depleted of Zic2a (B) show a typical reduction of PT relative to control morphants (A). (C) Homozygous syut4 mutant embryos show reduction of PT dlx2a (9/35 embryos, 2 exp.). (D) syu14 mutants depleted of Zic2a exhibit an almost complete loss of dlx2a in the PT (17/74 embryos, 3 exp.). (E) homozygous smob641 embryos show reduced dlx2a expression in the PT (25/83 embryos, 3 exp.). (F) smob641 mutants depleted of Zic2a show complete loss of dlx2a in the PT (60/195 embryos, 4 exp.). Embryos are shown in lateral view, anterior to the left. Arrows point to the PT.