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. 2007 Sep 4;4(3):209–217. doi: 10.1080/15476910701385570

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© 2007 Informa USA, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 3 — Interpretation of the AlloMap test score depends on a clinically specified threshold. The clinician interprets the AlloMap score relative to a pre-selected threshold on the 0-to-40 scale and the associated negative predictive value. A score below the threshold indicates a low risk for acute cellular rejection (ACR), thus ruling out ACR. A score above the threshold suggests an increased risk for moderate-to-severe (≥3A/2R) ACR. By understanding the patient's clinical course, the time-dependent ACR risk, the clinical tolerance for false-negative or false-positive results, and practice-specific demographics, clinicians may personalize the management of heart transplant patients through the selection of the AlloMap threshold.