Table 1.
HLA-DRB1 allele phenotype frequencies in sporadic MS patients and controls
| Allele | MS, n = 163 | Control, n = 202 | MS vs. control |
|
|---|---|---|---|---|
| P value | OR (95% C.I.) | |||
| 1 | 23 (14%) | 41 (20%) | NS | |
| 4 | 39 (24%) | 59 (29%) | NS | |
| 7 | 25 (15%) | 49 (24%) | NS | |
| 8 | 11 (6.7%) | 9 (4.5%) | NS | |
| 9 | 1 (0.61%) | 7 (3.5%) | NS | |
| 10 | 1 (0.61%) | 2 (0.99%) | NS | |
| 11 | 13 (7.9%) | 31 (15%) | 0.050 | 0.51 (0.26–0.98) |
| 12 | 5 (3.1%) | 10 (5.0%) | NS | |
| 13 | 33 (20%) | 47 (23%) | NS | |
| 14 | 6 (3.7%) | 12 (5.9%) | NS | |
| 15 | 92 (56%) | 49 (24%) | <0.0001 | 3.00 (2.03–4.43) |
| 16 | 3 (1.8%) | 8 (4.0%) | NS | |
| 17 | 40 (25%) | 45 (22%) | NS | |
NS, not significant.