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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Am J Obstet Gynecol. 2008 Apr;198(4):466.e1–466.e11. doi: 10.1016/j.ajog.2007.12.031

Table 3.

Frequency of the neurodevelopmental outcomes according to markers of acute inflammation in the placenta and umbilical cord among the cohort (n=261).

Characteristics IQ<70 (%) P value CP (%) P Value Major* ND (%) P Value
Placenta:
Histologic chorioamnionitis
 Yes 13.5 0.251 4.1 0.842 19.3 0.628
 No 18.8 4.7 21.8
Acute inflammation - Membranes
 Yes 12.8 0.229 4.5 0.978 19.3 0.670
 No 18.5 4.6 21.5
Acute inflammation – Fetal Plate
 Yes 12.6 0.221 4.1 1.000 17.9 0.384
 No 18.5 4.8 22.5
Funisitis
 Yes 10.1 0.061 4.9 0.756 16.5 0.224
 No 19.6 4.3 23.2
Culture positive (any microbe)
 Yes 15.7 0.761 3.8 0.588 18.7 0.389
 No 17.1 5.2 23.1
Cord Blood:
Elevated IL-6
 Yes 9.6 0.275 3.9 0.633 13.5 0.314
 No 15.9 2.4 19.8
UU/Mycoplasma positive
 Yes 15.7 0.713 0.0 0.342 17.7 0.909
 No 13.6 4.1 18.4
*

Two children were not evaluated

IQ = Intelligence Quotient

CP = Cerebral Palsy

ND = Neurodevelopmental disability

UU = Ureaplasma Urealyticum