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. 2008 May 19;5:17. doi: 10.1186/1742-2094-5-17

Figure 1.

Figure 1

Effects of COX-2 deficiency on LPS-induced neuronal degeneration. Representative photomicrographs of FluoroJade-B staining in the hippocampus of COX-2+/+ and COX-2-/- mice 24 h after icv injection of LPS or vehicle. High magnification (10×) images of FluoroJade-B staining in the hippocampus are shown. The inset shows details of the neurons stained by FluoroJade-B in the hippocampus of COX-2-/- mice 24 h after icv injection of LPS (40× magnification). Bars represent 100 μm.