Table 1. Characteristics of the patients (N=102).
| No. of patients | % | |
|---|---|---|
| Age (years) | ||
| Median | 59 | |
| Range | 25–73 | |
| Sex | ||
| Male | 54 | 52.9 |
| Female | 48 | 47.1 |
| Performance status | ||
| ECOG 0 | 51 | 50.0 |
| ECOG 1 | 43 | 42.2 |
| ECOG 2 | 8 | 7.8 |
| Histology | ||
| WDA | 38 | 37.3 |
| PDC | 50 | 49.0 |
| SCC | 4 | 3.9 |
| UN | 10 | 9.8 |
| Extension | ||
| Locoregional | 28 | 27.5 |
| Disseminated | 74 | 72.5 |
| Topography | ||
| Supradiaphragmatic | 30 | 29.4 |
| Subdiaphragmatic | 29 | 28.4 |
| Both sides | 43 | 42.2 |
| Number of involved sites | ||
| 1 | 29 | 28.4 |
| 2 | 31 | 30.4 |
| 3 | 17 | 16.7 |
| ⩾4 | 25 | 24.5 |
| Number of metastases | ||
| 1 | 13 | 12.7 |
| 2 | 6 | 5.9 |
| 3 | 12 | 11.8 |
| ⩾4 | 71 | 69.6 |
| Main involved sites | ||
| Supraclavicular nodes | 28 | 27.5 |
| Hylomediastinal nodes | 26 | 25.5 |
| Abdominal nodes | 20 | 19.6 |
| Bone | 31 | 30.4 |
| Liver | 27 | 26.5 |
| Lung | 22 | 21.6 |
| Ascites | 12 | 11.8 |
| Pleural effusion | 10 | 9.8 |
| Nodes/soft tissues only | 42 | 41.2 |
| Visceral/bone involvement | 60 | 58.8 |
| Main symptoms | ||
| Pain | 65 | 63.7 |
| Gastrointestinal | 30 | 29.4 |
| Respiratory | 20 | 19.6 |
| Fever | 16 | 15.7 |
| Weight loss >10% | 9 | 8.8 |
| Laboratory parameters | ||
| Hb <12 | 28 | 27.5 |
| Any liver index ⩾1.25 × N | 42 | 41.2 |
| ALP ⩾1.25 × N | 21/95 | 22.1 |
| LDH ⩾1.25 × N | 26/86 | 30.2 |
| CEA >5 | 36/96 | 37.5 |
| CA 19.9>40 | 25/84 | 29.8 |
| CA 125>40 | 33/69 | 47.8 |
| Any epithelial marker abnormal | 62 | 60.8 |
| Any germ cell marker abnormal | 9 | 8.8 |
ECOG=Eastern Cooperative Oncology Group; WDA=well-differentiated adenocarcinoma; PDC=poorly differentiated carcinoma or adenocarcinoma; SCC=squamous cell carcinoma; UN=undifferentiated neoplasms. ALP=alkaline phosphatase; LDH=lactate dehydrogenase; CEA=carcino embrionic antigen; CA 19.9 and CA 125=carbohydrate antigens CA 19.9 and CA 125.