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. 2004 Apr 27;90(10):1955–1960. doi: 10.1038/sj.bjc.6601828

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Copyright © 2004 Cancer Research UK

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The immunohistochemical localisation of L-FABP in colon cancer, colon adenomas and normal colon. In colon cancer there is patchy staining of the tumour cells. (A) Tumour with a high proportion of tumour cells staining positively for L-FABP while (B) is a tumour with a low proportion of L-FABP positive tumour cells. The patchy or mosaic staining for L-FABP is also demonstrated in (B). (C) Tumour that is negative for L-FABP. A small tubular adenoma (D) showing patchy staining for L-FABP. In a villous adenoma (E) there is only a small proportion of tumour cells showing L-FABP immunoreactivity and the staining is in discrete groups of cells. Immunohistochemical staining for L-FABP in normal colon is present in the surface epithelium and the upper half of the crypt epithelium (F).