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. 2004 Apr 27;90(10):2032–2041. doi: 10.1038/sj.bjc.6601825

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Copyright © 2004 Cancer Research UK

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BIACORE experiments: (A) binding kinetics of anti-Id scFv 40, 69 and irrelevant scFv on trastuzumab F(abi′)₂ fragments immobilised on a CM5 sensor chip and equilibrium affinity constants (inserted Table), (B) inhibition of HER-2/neu ECD-Fc fusion protein binding on trastuzumab F(ab′)₂ fragments immobilised on a CM5 sensorchip by anti-Id scFv 69.