Table 3. Specialist and nonspecialist treatment of the axilla and breast, adequacy of treatment and relative risk of recurrence.
Specialists |
Nonspecialists |
||||
---|---|---|---|---|---|
No. | % | No. | % | P-value | |
Treatment of the Breast | |||||
Conservation Surgery | 462/906 | 51.0 | 572/1242 | 46.1 | 0.026 |
Inadequate conservation | 104 | 22.5 | 285 | 49.8 | <0.001 |
Local recurrence ratea | 7% | 14% | <0.001 | ||
RHR local recurrenceb | 1.00 | 1.54 | <0.001 | ||
(1.10–2.20) | |||||
Staging of the axilla | |||||
Rate of axillary staging | 843/906 | 93.0 | 984/1242 | 79.2 | <0.001 |
Inadequate staging | 69/906 | 7.6 | 503/1242 | 40.5 | <0.001 |
Treatment of the axilla | |||||
Inadequate treatment | 40/906 | 4.4 | 468/1242 | 37.7 | <0.001 |
Axillary recurrence rateb | 6% | 11% | <0.001 | ||
RHR axillary recurrenceb | 1.00 | 2.06 | <0.001 | ||
(1.48–2.88) | |||||
Systemic treatment | |||||
Premenopausal women | |||||
Chemotherapy (CT) rate | 72/238 | 30.3 | 49/326 | 15.0 | <0.001 |
Endocrine therapy (ET) rate | 102/238 | 42.9 | 170/326 | 52.1 | 0.033 |
CT or ET in prognostically poorc | 84/101 | 83.2 | 98/127 | 77.2 | 0.320 |
Postmenopausal women | |||||
Endocrine therapy rate | 518/668 | 77.5 | 723/916 | 78.9 | 0.537 |
CT or ET in prognostically poorc | 241/282 | 85.5 | 276/332 | 83.1 | 0.440 |
Actuarial estimate at 8 years.
After adjustment for nodal status, tumour size and histological prognostic grade.
Tumours greater than 40 mm, node positive or poor histological prognostic group.