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. 2004 May 25;90(12):2402–2410. doi: 10.1038/sj.bjc.6601888

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Copyright © 2004 Cancer Research UK

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(A) Inhibition of binding of biotinylated CM79 antibody by sera of patients after administration of MFECPHis and A5CP. Binding of CM79 antibody in immunised sera was compared to CM79 antibody binding in normal human serum. Statistical comparison of the reduction of CM79 antibody binding after treatment with A5CP with the reduction of CM79 antibody binding after treatment with MFECPHis was significant (P=0.00003 for the comparison of all available sera after administration of MFECPHis and A5CP; P=0.023 for the comparison of HACA-positive sera only, unpaired Student's t-test). (B) Results were confirmed on CP-coated plates (P=0.0001 for the comparison of all available sera after administration of MFECPHis and A5CP, P=0.03 for the comparison of HACA-positive sera only, unpaired Student's t-test). Bars indicate standard deviation.