Skip to main content
. 2004 May 4;90(12):2338–2343. doi: 10.1038/sj.bjc.6601845

Table 2. Association of (A) tumour TP changes and (B) stromal TP changes with patients' characteristics.

(A) Tumour TP changes
  Tumour TP
  Up (%) NC (%) Down (%) P-value*
Menopausal status        
 Pre 29 (63.0) 9 (19.6) 8 (17.4)  
 Post 21 (45.7) 18 (39.1) 7 (15.2) 0.122
         
Tumour size        
 Median (range) 6.2 (1.5–18.0)      
 −3.0 cm 6 (54.6) 2 (18.2) 3 (27.3)  
 3.1 cm – 44 (54.3) 25 (30.9) 12 (14.8) 0.456
         
Number of nodes involved        
 0 13 (68.4) 5 (26.3) 1 (5.3)  
 1–3 9 (50.0) 5 (27.8) 4 (22.2)  
 4– 28 (50.9) 17 (30.9) 10 (18.2) 0.578
         
Oestrogen receptor        
 Positive 36 (61.0) 16 (27.1) 7 (11.9)  
 Negative 14 (42.4) 11 (33.3) 8 (24.2) 0.157
         
(B) Stromal TP changes
  Stromal TP
  Up (%) NC (%) Down (%) P-value*
Menopausal status        
 Pre 15 (32.6) 16 (34.8) 15 (32.6)  
 Post 15 (32.6) 17 (37.0) 14 (30.4) 1.000
         
Tumour size        
 Median (range) 6.2 (1.5–18.0)      
 −3.0 cm 0 (0.0) 7 (63.6) 4 (36.4)  
 3.1 cm– 30 (37.0) 26 (32.1) 25 (30.9) 0.020
         
Number of nodes involved        
 0 10 (52.6) 3 (15.8) 6 (31.6)  
 1–3 4 (22.2) 9 (50.0) 5 (27.8)  
 4– 16 (29.1) 21 (38.2) 18 (32.7) 0.173
         
Oestrogen receptor        
 Positive 21 (35.6) 20 (33.9) 18 (30.5)  
 Negative 9 (27.3) 13 (39.4) 11 (33.3) 0.736

TP=thymidine phosphorylase; Up=upregulated; NC=no change; Down=downregulated;

*

Fisher's exact test.