Table 2. Association of (A) tumour TP changes and (B) stromal TP changes with patients' characteristics.
(A) Tumour TP changes | ||||
---|---|---|---|---|
Tumour TP |
||||
Up (%) | NC (%) | Down (%) | P-value* | |
Menopausal status | ||||
Pre | 29 (63.0) | 9 (19.6) | 8 (17.4) | |
Post | 21 (45.7) | 18 (39.1) | 7 (15.2) | 0.122 |
Tumour size | ||||
Median (range) | 6.2 (1.5–18.0) | |||
−3.0 cm | 6 (54.6) | 2 (18.2) | 3 (27.3) | |
3.1 cm – | 44 (54.3) | 25 (30.9) | 12 (14.8) | 0.456 |
Number of nodes involved | ||||
0 | 13 (68.4) | 5 (26.3) | 1 (5.3) | |
1–3 | 9 (50.0) | 5 (27.8) | 4 (22.2) | |
4– | 28 (50.9) | 17 (30.9) | 10 (18.2) | 0.578 |
Oestrogen receptor | ||||
Positive | 36 (61.0) | 16 (27.1) | 7 (11.9) | |
Negative | 14 (42.4) | 11 (33.3) | 8 (24.2) | 0.157 |
(B) Stromal TP changes | ||||
Stromal TP |
||||
Up (%) | NC (%) | Down (%) | P-value* | |
Menopausal status | ||||
Pre | 15 (32.6) | 16 (34.8) | 15 (32.6) | |
Post | 15 (32.6) | 17 (37.0) | 14 (30.4) | 1.000 |
Tumour size | ||||
Median (range) | 6.2 (1.5–18.0) | |||
−3.0 cm | 0 (0.0) | 7 (63.6) | 4 (36.4) | |
3.1 cm– | 30 (37.0) | 26 (32.1) | 25 (30.9) | 0.020 |
Number of nodes involved | ||||
0 | 10 (52.6) | 3 (15.8) | 6 (31.6) | |
1–3 | 4 (22.2) | 9 (50.0) | 5 (27.8) | |
4– | 16 (29.1) | 21 (38.2) | 18 (32.7) | 0.173 |
Oestrogen receptor | ||||
Positive | 21 (35.6) | 20 (33.9) | 18 (30.5) | |
Negative | 9 (27.3) | 13 (39.4) | 11 (33.3) | 0.736 |
TP=thymidine phosphorylase; Up=upregulated; NC=no change; Down=downregulated;
Fisher's exact test.