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. 2004 Jan 20;90(2):353–358. doi: 10.1038/sj.bjc.6601472

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Copyright © 2003 Cancer Research UK

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OS curves for patients grouped according to the AUC_MTX. Patients treated with an AUC_MTX >1100 μmol h l⁻¹ (continued line) showed a significantly better survival with respect to those treated with an AUC_MTX ⩽1100 μmol h l⁻¹ (dotted line).