. 2004 Jan 20;90(2):353–358. doi: 10.1038/sj.bjc.6601472

Table 3. Correlations between AUC_MTX and the other analysed variables.

Variables	Subgroups	No.	AUC_MTX (mean±s.d. μmol h l⁻¹)	P
Age	⩽60 years	30	846±562
	>60 years	15	502±359	0.02

Sex	Females	16	540±398
	Males	29	837±562	0.08

PS	0–1	19	927±614
	2–4	26	589±405	0.08

Anticonvulsants	No	14	1028±662
	Yes	31	598±394	0.04

IR_MTX (mg m⁻² h⁻¹)	⩽800	33	635±564
	>800	12	996±274	0.003

DI_MTX (mg m⁻² week⁻¹)	⩽1000	33	559±392
	>1000	12	1206±567	0.0003

CL_crea (ml min⁻¹)	⩽85	12	604±434
	>85	33	778±553	0.35


Chemotherapy regimen	HD-MTX	10	857±658
	MATILde	11	1043±240
	MTX+AraC	24	536±491	0.008

PS=performance status according to the ECOG score.

Table 3. Correlations between AUCMTX and the other analysed variables.