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COX-2 expression in normal and neoplastic breast tissue. For each tissue, the thick black horizontal bars represent the median COX-2 score, the boxes represent the interquartile range and the T-bars the full range. The median COX-2 expression in neoplastic DCIS and invasive cancer epithelium are significantly greater than in normal breast ducts (P<0.0001), although there was no difference between DCIS and invasive cancer in median expression (P=0.59).
