Table 2. Univariate survival analysis of established prognostic features and of the −174G/C IL-6 genotype.
| Feature | Relative risk (95% CI) | P |
|---|---|---|
| −174G/C IL-6 genotype1 | 1.99 (1.05–3.77) | 0.034 |
| Nodal involvement | 2.44 (1.66–3.57) | <0.001 |
| Histological grade | 3.28 (1.84–5.85) | <0.001 |
| Tumour size | 4.44 (2.19–9.00) | <0.001 |
| Tumour type | 1.24 (0.62–2.51) | NS |
| Oestrogen receptor | 1.05 (0.82–1.33) | NS |
| Progesterone receptor | 1.03 (0.82–1.30) | NS |
| Ploidy | 0.99 (0.58–1.70) | NS |
| ErbB2 amplification | 2.05 (1.04–4.03) | 0.037 |
CC vs CG/GG genotypes. For all other factors, the groups compared are the same as those shown in Table 1.