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. 2004 Feb 3;90(3):728–735. doi: 10.1038/sj.bjc.6601585

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Copyright © 2004 Cancer Research UK

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K_m curves for involucrin (solid circles) and pimonidazole binding (open circles) in SCC9 cells exposed for 2 h to different pO₂ in the presence of 1.0 mM calcium ion concentration. The data represent averages of two independent experiments. Range of data for the two experiments is shown where it exceeded the dimension of the data symbol. Note the 40-fold difference in K_m between involucrin induction and pimonidazole binding and the steep pO₂ dependence for involucrin induction.