Table 2. Distribution of prognostic factors.
Consecutive patients |
Evaluable patients |
Baseline patients |
Week-5 patients |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Prognostic group | n=49 | % | n=46 | % | P | n=34 | % | P | n=25 | % | P |
(a) MSKCCa | |||||||||||
Favourable | 3 | 6% | 3 | 7% | 0.66 | 2 | 6% | 0.70 | 2 | 8% | 0.59 |
Intermediate | 25 | 51% | 24 | 52% | 16 | 47% | 14 | 56% | |||
Poor | 21 | 43% | 19 | 41% | 16 | 47% | 9 | 36% | |||
(b) UISSb | |||||||||||
Baseline patients | Week-5 patients | ||||||||||
n=34 | % | n=25 | % | P | |||||||
UISS 3 | 6 | 18% | 5 | 20% | 1.00 | ||||||
UISS 4 | 27 | 79% | 19 | 76% | |||||||
UISS 5 | 1 | 3% | 1 | 4% |
P=Fisher's exact test.
Motzer et al (1999). Risk factors: Karnofsky PS <80, LDH ⩾1.5 times upper limit of normal, haemoglobin <lower limit of normal, corrected s-Ca >10 mg dl−1 or ion-Ca >upper limit of normal and no prior nephrectomy. No risk factors=favourable prognosis, 1–2 risk factors=intermediate prognosis and >2 risk factors=poor prognosis.
UCLA Integrated Staging System (Zisman et al, 2001), based on TNM stage, Fuhrman grade and performance status.