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. 2004 Mar 2;90(5):1030–1033. doi: 10.1038/sj.bjc.6601647

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Copyright © 2004 Cancer Research UK

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Representative MSP of CDH13 promoter in colorectal cancer cell lines (SW1083, SW1116, and SW1417) and oesophageal cancer cell line (TE1). The presence of a visible PCR product in lane U indicates the presence of unmethylated genes; the presence of PCR product in lane M indicates the presence of methylated genes. All three colorectal cancer cell lines that demonstrated only methylation of the CDH13 promoter lacked CDH13 gene expression as determined by RT–PCR, while CDH13 was expressed in TE1 with unmethylation of the CDH13 promoter.

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