Table 1. Clinicopathological features and methylation status of CDH13 promoter region in colorectal cancer patients.
No. of cases |
CDH13 methylation |
|||
---|---|---|---|---|
Clinicopathological variable features | + | − | P-value | |
Sex | ||||
Male | 45 | 18 | 27 | 0.098a |
Female | 39 | 9 | 30 | |
Maximal tumour size | ||||
15–100 mm | 84 | 50.9±21.3b | 45.2±16.5 | 0.182c |
Histology | ||||
Poorly differentiatedd | 6 | 5 | 1 | 0.0053a |
Other differentiatede | 78 | 22 | 56 | |
Extent of tumour | ||||
≦mtf | 20 | 6 | 14 | 0.814a |
mt< | 64 | 21 | 43 | |
Lymph node metastasis | ||||
+ | 31 | 6 | 25 | 0.055a |
− | 53 | 21 | 32 | |
Dukes' stage | ||||
A, B | 54 | 19 | 35 | 0.423a |
C, D | 30 | 8 | 22 | |
Total | 84 | 27 | 57 |
χ2 test.
Mean±s.d.
Student's t-test.
Poorly differentiated or mucinous adenocarcinoma according to Japanese criteria.
Well- or moderately differentiated adenocarcinoma according to Japanese criteria.
Muscular tunic.