Table 4. Response for phase I/II.

Dose level	n	CR	PR	SD	PD	NE	ORR (%)
Phase 1
Level 1	3(2)	—	1(1)	2(1)	0	0	33.3
Level 2	6(3)	—	4(3)	1(0)	0	1(0)	67.8
Level 3	3(1)	—	2(1)	0	1(0)	0	67.8
Level 4	6(1)	—	5(0)	0	1(1)	0	83.3
Total	18(7)	—	12(5)	3(1)	2(1)	1(0)	70.6
Phase II	20(0)	1(0)	11(0)	6(0)	2(0)	0(0)	55.0
Phase I/II	38(7)	1(0)	23(5)	9(1)	2(1)	1(0)	62.1

(): number of pretreated patients, n=number of patients, CR=complete response, PR=partial response, SD=stable disease, PD=progression disease, NE=not evaluable, ORR=objective response rate.