Table 2. Overview of all HBOC and FBOC families investigated and mutation detection frequencies.

		FBOC				HBOC
			#mutations found (%)				#mutations found (%)
Phenotypes		N	BRCA1	BRCA2	BRCA	N	BRCA1	BRCA2	BRCA
Breast–ovarian cancer	No male breast cancer patient	39	9 (23.1%)	0	9 (23.1%)	25	13 (52.0%)	6 (24.0%)	19 (76.0%)
families	At least one male breast cancer patient	0	0	0	0	3	0	2 (66.7%)	2 (66.7%)
	Total	39	9 (23.1%)	0	9 (23.1%)	28	13 (46.4%)	8 (28.6%)	21 (75.0%)
Breast cancer-only	No male breast cancer patient	155	13 (8.4%)	11 (7.1%)	24 (15.5%)	60	11 (18.3%)	3 (5.0%)	14 (23.3%)
families	At least one male breast cancer patient	6	0	2 (33.0%)	2 (33.0%)	3	0	1 (33.3%)	1 (33.0%)
	Total	161	13 (8.1%)	13 (8.1%)	26 (16.1%)	63	11 (17.5%)	4 (6.3%)	15 (23.8%)
Total		200	22 (11.0%)	13 (6.5%)	35 (17.5%)	91	24 (26.4%)	12 (13.2%)	36 (39.6%)

FBOC=familial breast and/or ovarian cancer; HBOC=hereditary breast and/or ovarian cancer.