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. 2004 Feb 24;90(6):1138–1143. doi: 10.1038/sj.bjc.6601662

Table 1. Prognostic factor analysis of 2192 women with breast cancer, ORCC, 1994–1997.

  Univariate analysis
Multivariate analysisa
  Univariate analysis
Multivariate analysisa
Variables RER (95% CI) P-valueb RER (95% CI) P-valueb Variables RER (95% CI) P-valueb RER (95% CI) P-valueb
Stage   0.00000   0.00000 Age (years)   0.00005   0.00004
 Stage I 1.00   1.00    0–39 1.00   1.00  
 Stage II 4.54 (2.32,8.89)   3.05 (1.55,5.99)    40–49 0.45 (0.29,0.68)   0.46 (0.30,0.71)  
 Stage III 15.64 (7.78,31.44)   8.28 (4.08,16.83)    50–69 0.29 (0.19,0.44)   0.45 (0.31,0.69)  
 Stage IV 52.35 (26.74,82.47)   25.80 (12.88,51.65)    70+ 0.47 (0.29,0.75)   0.85 (0.55,1.31)  
Treatment   0.00000   0.00592 Histology   0.00257   0.08866
 Chemotherapy 1.00   1.00    Ductal carcinoma 1.00   1.00  
 Radiotherapy 0.15 (0.06,0.40)   0.97 (0.42,2.23)    Lobular carcinoma 0.50 (0.24,1.01)   0.66 (0.37,1.16)  
 Surgery 0.12 (0.06,0.25)   0.47 (0.24,0.94)    Others 1.76 (1.16,2.66)   1.18 (0.80,1.74)  
 C+Rc 0.74 (0.44,1.27)   1.07 (0.63,1.81)   Grade   0.00000   0.00007
 S+Cc 0.25 (0.18,0.36)   0.58 (0.39,0.86)    Grade 1 1.00   1.00  
 S+Rc 0.02 (0.01,0.12)   0.35 (0.15,0.81)    Grade 2 7.26 (1.77,29.72)   2.68 (1.00,7.15)  
 S+C+Rc 0.19 (0.11,0.30)   0.53 (0.33,0.85)    Grade 3 18.37 (4.55,74.16)   4.87 (1.84,12.87)  

Relative survival rate (RER) estimated according to regression models based on relative survival.

a

Adjusted for all the other variables in the table.

b

P-value from likelihood ratio test.

c

C=chemotherapy; R=radiotherapy; S=surgery.