Table 2. Relative 5-year survival of breast cancer patients by age group, TNM stage, histology, grade and treatment from univariate analysis, ORCC, 1994–1997.
| No. (%)a | Relative survival (%) | ||
|---|---|---|---|
| Prognostic factor | observations | Rate | 95% CIb |
| Age at diagnosis (years) | |||
| 0–39 | 147 (6.7) | 69.9 | 60.5–77.5 |
| 40–49 | 448 (20.4) | 84.2 | 79.3–88.1 |
| 50–69 | 972 (44.3) | 88.4 | 84.9–91.4 |
| 70+ | 625 (28.5) | 81.3 | 74.9–86.2 |
| TNM stagec | |||
| Stage I | 812 (37.0) | 96.0 | 92.7–97.8 |
| Stage II | 843 (38.5) | 85.6 | 81.7–88.7 |
| Stage III | 155 (7.1) | 59.2 | 47.9–68.9 |
| Stage IV | 112 (5.1) | 25.5 | 16.1–36.0 |
| Histology type | |||
| Ductal carcinoma | 1765 (80.5) | 84.32 | 81.6–86.7 |
| Lobular carcinoma | 233 (10.6) | 91.02 | 81.0–95.9 |
| Others | 194 (8.9) | 76.65 | 67.7–83.4 |
| Histologic gradec | |||
| G1 (well differentiated) | 346 (15.8) | 97.2 | 90.9–99.1 |
| G2 (moderately differentiated) | 674 (30.8) | 87.8 | 83.7–91.0 |
| G3 (poorly differentiated) | 474 (21.6) | 73.9 | 68.0–78.9 |
| Treatmentc | |||
| Chemotherapy | 38 (1.7) | 46.2 | 25.2–64.8 |
| Radiotherapy | 54 (2.5) | 87.7 | 73.1–94.7 |
| Surgery | 188 (8.6) | 89.1 | 77.2–94.9 |
| Chemotherapy+radiotherapy | 135 (6.2) | 61.4 | 51.3–70.1 |
| Chemotherapy+surgery | 396 (18.1) | 82.1 | 75.8–86.9 |
| Radiotherapy+surgery | 389 (17.8) | 96.0 | 89.7–98.6 |
| Chemotherapy+radiotherapy+surgery | 972 (44.3) | 77.4 | 73.3–80.9 |
a
P-value of χ2 test for the changes in a variable structure was less than 0.0001 for each variable considered.
b
CI=confidence interval.
c
Unstaged (%)=12.3, ungraded=31.8 and untreated or unknown=0.9.