Table 6. Hepatic toxicity – all grades.
| Cohort | Total no. of cycles | Toxicity no. of cycles (%) | Grade | |
|---|---|---|---|---|
| 1 | 18 | 0 | 0% | |
| 2 | 18 | 3 | 17% | I/II |
| 3 | 18 | 5 | 28% | I/II |
| 4 | 21 | 7 | 33% | I/II |
| 5 | 24% | III/IV | ||
| 3 repeat | 18 | 2 | 11% | I/II |
| Total | 93 | 22 | 24% | |
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