Skip to main content
. 2004 Mar 2;90(7):1349–1360. doi: 10.1038/sj.bjc.6601710

Table 1. Existing literature on the use of breast MRI to monitor response to chemotherapy.

Author Origin Year Number Measurement Pathology response
Knopp et al (1994) Heidelberg, Germany 1994 Three case studies   Promising prediction
Gilles et al (1994) Villejuif, France 1994 18   (15 out of 18) 83% Highly predictive of residual tumour
Abraham et al (1996) Dallas & Little Rock, USA 1996 39   MRI correctly predicted residual disease in 30 out of 31 (97%)
Rieber et al (1997) Ulm, Germany 1997 13   Underestimates residual tumour
Trecate et al (1998) Milano, Italy 1998 27   Valid tool for monitoring response
Tsuboi et al (1999) Kochi, Japan 1999 31   Valuable for predicting response and margins
Weatherall et al (2001) Dallas, TX, USA 2001 22 Cc0.93MR, 0.63 mam Accurate assessment of residual tumour
Nakamura et al (2001) Tokyo, Japan 2001 15   Predict possibility of WLE. Mapping of dendritic tumours
Drew et al (2001) Hull, UK 2001 17 Sensitivity 100% Accurate method of predicting residual tumour
Esserman et al (2001) UCSF 2001 33   Patterns of tumours identified
Partridge et al (2002) UCSF 2002 52 R0.89, C0.60 MRI detected all residual disease
Balu-Maestro et al (2002) Nice, France 2002 60 in 51 women   Valuable tool for size & multifocality prior to surgery
Rieber et al (2002) Ulm, Germany 2002 58 Accuracy NR 83.3%, PR 82.4% Good for assessing response to chemo, unreliable in CR cases where 66.7% had residual tumour
Cheung et al (2003) Kwei San, Taiwan 2003 33   Useful to assess early response and predict tumour size change
Delille et al (2003) Harvard, USA 2003 14 EFPcount accurate measure (P<.02) Extraction flow product as marker of tumour response