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. 2004 Mar 23;90(8):1620–1626. doi: 10.1038/sj.bjc.6601723

Figure 2.

Figure 2

Effect of ephrin-B2 overexpression on the growth of tumours from ephrin-B2-sense-transfected KM12L4 cells in nude mice. (A) Mean tumour volumes were determined every other day following subcutaneous injection (n=10). On days 7–15, the mean volumes of tumours from ephrin-B2-sense-transfected cells (S2 and S pool) were significantly smaller than those of control tumours from parental KM12L4 cells or vector-transfected cells (*P<0.0001, ANOVA). Error bars indicate the standard error (s.e.m.) of the mean. (B) After 15 days, the mice injected with ephrin-B2-sense-transfected KM12L4 cells (white bars) had significantly less heavy tumours than did control mice (black bars) (*P<0.0001, ANOVA). Error bars indicate s.e.m. of the mean.