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. 2004 Mar 23;90(8):1620–1626. doi: 10.1038/sj.bjc.6601723

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Copyright © 2004 Cancer Research UK

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Immunohistochemical staining H&E, CD31, and PCNA. Immunohistochemical staining with H&E (top row; × 100), CD31 (middle row; × 100), and PCNA (bottom row; × 100) was performed on tumour sections. Representative sections demonstrate more vessels and fewer PCNA positive cells in tumours from ephrin-B2-sense-transfected KM12L4 cells (columns 3 and 4). The vessels in the experimental tumours were morphologically distinct from normal vessels in that they were small and less prominent that those in control tumours (columns 1 and 2).