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. 2004 Apr 13;90(9):1710–1714. doi: 10.1038/sj.bjc.6601783

Table 2. World Health Organization (WHO) toxicities (number of patients=29).

  Number of events (%) Grade 1 N (%) Grade 2 N (%) Grade 3 N (%) Grade 4 N (%)
Hematological 11 (37.9%)        
 Anaemia 4 (13.8%) 2 (6.9%) 2 (6.9%)    
 Neutropenia 6 (20.6%) 1 (3.45%) 2 (6.9%) 3 (10.3%)  
 Thrombocytopenia 1 (3.45%)       1 (3.45%)
           
Gastroenteric toxicity 7 (24.1%)        
 Nausea/vomiting 2 (6.9%) 1 (3.45%)     1 (3.45%)
 Diarrhoea 2 (6.9%) 1 (3.45%)     1 (3.45%)
 Mucositis 3 (10.3%) 2 (6.9%)     1 (3.45%)
           
Transaminase elevation None        
Fever 8 (27.6%) 3 (10.3%) 5 (17.2%)    
Asthenia 2 (6.9%)     1 (3.45%) 1 (3.45%)
Anorexia None        
Neurological toxicity 2   2 (6.9%)    
Arrythmia 2   2(6.9%)    
Hypersensitivity 3 (10.3%) 1 (3.45%) 1 (3.45%) 1 (3.45%)  

A total of 296 chemotherapy cycles were administered (a median range of 10 cycles per patient).