Table 4. Comparison between SmCC arising at different GI sites (n=64).
| Upper GIT (n=24) | Lower GIT (n=27) | Other (n=13) | |
|---|---|---|---|
| Median age (years) | 65 | 55 | 59 |
| Male gender | 17/24 (71) | 9/27 (33) | 5/13 (38) |
| Second malignancies | 6/22 (27) | 1/22 (5) | 4/10 (40) |
| Mixed histology | 9/23 (39) | 10/27 (37) | 4/12 (33) |
| Extensive disease | 10/23 (43) | 13/27 (48) | 7/13 (54) |
| Response to chemotherapy | 3/8 (37) | 3/9 (33) | 2/5 (40) |
| Progression rate | 18/21 (86) | 20/21 (95) | 10/13 (77) |
GIT: gastrointestinal tract; SmCC=small-cell carcinoma.
a
Tumours were grouped into three categories: upper GIT (oesophagus, GEJ and stomach), lower GIT (large bowel and anus) and other (hepatobiliary system and small bowel).