Figure 2.

(A) Loss of heterozygosity in cancer A but not in cancer B at the D3S1300 locus as detected by microsatellite analysis. (B) Loss of heterozygosity at the rs722070 locus by SNP analysis. Results of a representative experiment involving 33 test samples. □, Homozygous cases or heterozygous cases showing no LOH. ▪, Five heterozygous cases showing LOH in the cancer, confirmed by repeat testing. —, Positive controls for allele 1, allele 2 and alleles 1+2 (supplied by the manufacturer) tested in triplicate. ▴, Nine control samples previously tested and confirmed to be homozygous or heterozygous at this locus.