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. 2004 Dec 21;91(12):2094–2100. doi: 10.1038/sj.bjc.6602243

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Copyright © 2004 Cancer Research UK

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Optical density (OD) of MIA cultures after 72 h dose-escalating CP-320626 treatment in the MTS cell proliferation/survival assay. This test indicates significantly fewer MIA cells with deprived oxidative metabolism after increasing doses of CP-320626 treatment. This experiment was performed in comparison with 2-deoxy-D-glucose, which is a well-known growth-inhibitory substrate through cell cycle arrest and apoptosis (n=8; mean±s.d.; ^*P<0.05, ^**P<0.01).