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. 2004 Dec 21;91(12):2094–2100. doi: 10.1038/sj.bjc.6602243

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Copyright © 2004 Cancer Research UK

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Continued SIDMAP reflecting decreased fatty acid synthesis in MIA cells after treatment with increasing doses of the glycogen phosphorylase inhibitor CP-320626. In control cultures, about 18% of acetyl units and about 52% of intracellular palmitate arise from glucose, expressed as per cent (%) of the total. CP-320626 treatment decreased both acetyl unit synthesis and de novo fatty acid palmitate synthesis from glucose in a dose-dependent fashion (n=6; mean+s.d.; ^*P<0.05, ^**P<0.01).