Table 2. Association of genomic polymorphisms with ethnicity.

		Ethnicity
		Caucasian		Hispanic		Black		Asian
Factors	No. of patients	N	%	N	%	N	%	N	%	P-value*
XPD-751										<0.001
Lys/Lys	40	19	25	8	57	4	67%	10	91
Lys/Gln	53	46	61	4	29	2	33%	1	9
Gln/Gln	13	11	14	2	14	0	0%	0	0
XPD-156										0.14
A/A	14	12	16	1	8	0	0%	1	9
C/A	59	43	58	7	54	1	17%	8	73
C/C	30	19	26	5	38	5	83%	2	18
Unknown	3	2		1
XPA-5′										0.14
G/G	24	18	27	4	33	3	60%	0	0
A/G	53	37	56	7	58	2	40%	7	64
A/A	16	11	17	1	8	0	0%	4	36
Unknown	13	10		2		1
ERCC1-118										0.002
C/C	30	15	20	6	43	6	100	4	36
C/T	45	34	45	5	36	0	0	6	55
T/T	31	27	36	3	21	0	0	1	9
XRCC1-399										0.63
Arg/Arg	44	29	39	5	36	3	50	7	64
Gln/Arg	51	39	52	8	57	2	33	3	27
Gln/Gln	10	7	9	1	7	1	20	1	9
Unknown	1	1
TS-3′UTR										0.030
+6BP/+6BP	37	31	42	4	31	1	17	1	9
+6BP/−6BP	52	35	48	9	69	3	50	6	55
-6BP/−6BP	13	7	10	0	0	2	33	4	36
Unknown	4	3		1
TS-5′UTR										0.25
3R/3R	43	30	39	4	31	1	17	8	73
2R/3R	46	34	45	7	54	3	50	3	27
2R/2R	16	12	16	2	15	2	33	0	0
2/4	1			1
GSTP1-105										0.61
Val/Val	10	7	9	1	7	1	17	1	9
Ile/Val	47	35	46	6	43	4	67	3	27
Ile/Ile	49	34	45	7	50	1	17	7	64
GSTT1										1.00
Positive	75	53	72	10	77	4	80	8	73
Negative	27	21	28	3	23	1	20	3	27
Unknown	4	2		1		1
GSTM1										0.14
Positive	54	39	53	9	69	4	80	3	27
Negative	48	35	47	4	31	1	20	8	73
Unknown	4	2		1		1

GSTP=glutathione S-transferase; TS=thymidylate synthase; UTR=untranslated region.

^*P-value is based on Fisher's exact test.