Table 2. Labelling indices – descriptive statistics.
| Grade | Statistic | Ki67 | Mcm2 | AI | Csp3 | p21 | G92 | G95 |
|---|---|---|---|---|---|---|---|---|
| II | Mean (s.d.) | 11.4 (8.5) | 16.0 (15.3) | 0.8 (0.5) | 1.8 (2.5) | 2.3 (2.7) | 2.5 (1.8) | 2.4 (1.9) |
| Median (IQR) | 8.8 (11.7) | 10.2 (16.8) | 0.6 (0.8) | 0.9 (1.6) | 1.5 (3.4) | 2.5 (2.5) | 2.3 (2.8) | |
| III | Mean (s.d.) | 22.1 (16.3) | 40.0 (25.1) | 1.1 (0.7) | 2.4 (2.5) | 4.4 (5.4) | 8.9 (9.8) | 8.5 (6.9) |
| Median (IQR) | 21.3 (18.2) | 37.8 (44.6) | 0.9 (0.8) | 1.6 (3.2) | 3.2 (4.5) | 6.4 (5.1) | 6.4 (7.2) | |
| P-value* | 0.002 | <0.001 | 0.058 | 0.335 | 0.061 | <0.001 | <0.001 |
AI=apoptosis index based on H&E counts, IQR=interquartile range, P-value*=for grade III vs grade II tumours, Mann–Whitney U-test.