Table 3. Cutoff threshold levels for background aneusomy (percentage) for the six chromosomes examined in series 1 (1994–1998).
|
Signal number category |
||||
|---|---|---|---|---|
| 1 | 3 | 4 | >4 | |
| Chromosome 7 | 11.5 | 0.6 | 0.7 | 0.2 |
| Chromosome 8 | 8.7 | 0.5 | 0.9 | 0.1 |
| Chromosome 11 | 11.2 | 0.4 | 1.2 | 0.2 |
| Chromosome 12 | 10.0 | 1.4 | 1.0 | 0.2 |
| Chromosome 17 | 13.4 | 0.9 | 1.0 | 0.1 |
| Chromosome 18 | 14.7 | 0.6 | 0.7 | 0.0 |
The presented cutoffs were determined by evaluation of non-disomy in 15 nonmalignant control effusions, and reflect the mean+3 s.d. percentage of aneusomic cells within each of four FISH signal categories (see Fiegl et al, 2000).