Table 3. Summary of complete responders and disease-free patients.
| Case no. | Age at IPDT (years) | Sex | Treatment site | Pathology | Stage original/recurrent | Previous treatment | Time from initial tx to IPDT (month) | Tumour volume (cm3) prior to PDT | Disease-free time (month) | Follow-up time (month) | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 52 | M | Neck | SCC | N3/N2 | R, S | 18 | 12 | 14 | 17 | LR |
| 2 | 57 | F | HP | SCC | T2/T4 | R | 30 | 32 | NER | 22 | UD |
| 3 | 60 | M | TB | SCC | T4/T4 | CR, B | 46 | 80 | 12 | 17 | LR |
| 4 | 82 | F | AR | SCC | T4/T2 | S, S | 5 | 8 | NER | 13 | AW |
| 5 | 21 | F | Tongue | SCC | T1/T3 | S, S | 24 | 12 | 26 | 32 | LR |
| 6 | 52 | M | FOM | SCC | T4/T3 | S, R | 5 | 10 | NER | 10 | AW |
| 7 | 59 | M | Tongue | SCC | T4/T4 | CR | 8 | 60 | NER | 28 | AW |
| 8 | 42 | F | Parotid | ACC | T4/T4 | S, R | 46 | 32 | NER | 15 | AW |
| 9a | 8 | F | HP | ASPS | T2B/T2B | C, S | 3 | 20 | NER | 60 | AW |
ACC: adenoid cystic carcinoma, AR: alveolar ridge, ASPS: alveolar soft part sarcoma, AW: alive and well, B: brachytherapy, C: chemotherapy, CR: chemoradiation, FOM: floor of mouth, HP: hard palate, LR: died of local recurrence of disease, NER: no evidence of recurrence at the last follow-up, R: radiotherapy, S: surgery, SCC: squamous cell carcinoma, TB: tongue base, tx: treatment, UD died of unrelated disease; IPDT=interstitial photodynamic therapy; PDT=photodynamic therapy.
a
Two IPDT treatments were performed to debulk the tumour followed by radiotherapy and local excision for persistent microscopic disease. Since then, she has been free of disease.