Table 3. Inhibition of tumour growth by GW654652, a VEGFR kinase inhibitor.

	% Inhibitiona
	10 mg kg−1	30 mg kg−1	100 mg kg−1	ED50(mg kg−1 day−1)
HT29	5	69	98	20±8
HCT116	18	59	71	21±8
HN5	24	46	83	28±10
SW620	12	44	74	46±11
PC3	NDb	21	48	108±50
A375P	NDb	14	49	114±54

^a% Inhibition of tumour growth compared to vehicle-treated animals.

^bNot detectable.

VEGFR=vascular endothelial growth factor receptor.