Table 2. Odds ratios and cumulative risks of lung cancer by age 75, for never-, ex- and current cigarette smokers, among men, by country.
| Country | Case/control | ORa | Standarda 95% CI | Floatingb 95% CI | Cumulative riskc (95% CI) |
|---|---|---|---|---|---|
| UKd | |||||
| Nonsmoker | 3/400 | 1.0 | 0.3–3.1 | 0.2 (0.01–0.4) | |
| Ex-smoker | 285/1106 | 34.4 | 10.9–107.5 | 30.2–39.1 | 5.7 (5.0–6.4) |
| Current smoker | 322/453 | 94.8 | 30.2–297.8 | 82.2–109.3 | 15.7 (14.4–17.0) |
| Germany | |||||
| Nonsmoker | 63/763 | 1.0 | 0.8–1.3 | 0.6 (0.4–0.7) | |
| Ex-smoker | 1059/1699 | 7.5 | 5.7–9.8 | 7.0–8.1 | 4.2 (4.0–4.5) |
| Current smoker | 2342/1039 | 27.3 | 20.9–35.6 | 25.4–29.4 | 14.3 (13.6–15.0) |
| Italy | |||||
| Nonsmoker | 18/277 | 1.0 | 0.6–1.6 | 0.6 (0.3–0.9) | |
| Ex-smoker | 520/716 | 11.2 | 6.8–18.2 | 10.0–12.5 | 6.5 (5.9–7.0) |
| Current smoker | 833/539 | 23.7 | 14.6–38.7 | 21.3–26.5 | 13.8 (12.8–14.8) |
| Sweden | |||||
| Nonsmoker | 36/706 | 1.0 | 0.7–1.4 | 0.4 (0.2–0.5) | |
| Ex-smoker | 263/813 | 6.3 | 4.4–9.1 | 5.5–7.3 | 2.3 (2.0–2.6) |
| Current smoker | 716/805 | 17.4 | 12.3–24.7 | 15.3–19.3 | 6.6 (6.2–7.0) |
a
Odds ratios and 95% confidence intervals calculated by logistic regression analyses, adjusted for age and centre.
b
95% confidence intervals are based on floating variance.
c
Cumulative risk expressed as percentage; 95% confidence intervals are based on floating variance.
d
UK estimates of cumulative risk differ slightly from those previously reported (Peto et al, 2000) due to use of incidence instead of mortality data. The OR for ex-smokers and current smokers in UK are also anomalously high by chance, due to the fact that the number of nonsmokers was unusually low by chance. This anomaly will have a minimal effect on the UK cumulative risks for current and ex-smokers. See text for an explanation.