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. 2004 Aug 24;91(7):1293–1300. doi: 10.1038/sj.bjc.6602134

Table 3. Univariate analysis of different clinicopathological factors for overall survival (OS) and disease-free survival (DFS).

    OS (months)     DFS (months)    
  n Median (s.e.b) 95% CIa P-value Median (s.e.) 95% CI P-value
Gender
 Male 241 77 (13) 51–103   Nr  
 female 38 Nrc 0.2677 84 (37) 12–156 0.8626
               
Histiotype
 Adenocarcinoma 93 59 (10) 40–78   Nr  
 Squamous 128 87 (11) 66–108 0.6150 Nr 0.4168
 Large cell 42 Nr 0.8902 Nr 0.8088
 other 16 Nr 0.7518 71 (44) 0–156 0.9604
               
Localisation
 Left 122 69 (12) 46–92   84 (30) 26–124  
 right 157 90 (11) 65–111 0.1260 Nr 0.1295
               
Type of operation
 (Bi)lobectomy 192 94 (12) 70–118   Nr  
 Pneumonectomy 87 35 (7) 21–49 0.0004 22 (6) 10–34 0.0005
               
T-status
 T1 89 94 (15) 64–124   102 (17) 68–136  
 T2 147 72 (15) 44–100 0.1050 Nr 0.0646
 T3 20 Nr 0.8880 Nr 0.2792
 T4 23 37 (9) 19–55 0.0151 18 (2) 15–21 0.0011
               
N-status
 N0 198 102 (10) 83–121   Nr  
 N1 64 39 (8) 23–55 0.0002 27 (12) 3–51 0.0009
 N2 17 29 (8) 13–45 0.0001 12 (3) 5–19 <0.0001
               
Stage
 St IA 77 94 (15) 65–123   Nr  
 St IB 90 90 (10) 70–110 0.6234 Nr 0.3330
 St IIA 12 46 (2) 41–51 0.0623 22 (21) 0–63 0.0135
 St IIB 60 58 (24) 12–104 0.0098 71 (28) 17–125 0.0055
 St IIIA 17 29 (7) 14–44 0.0001 12 (7) 0–25 <0.0001
 St IIIB 23 37 (9) 19–55 0.0045 18 (2) 15–21 0.0001
               
Radiotherapy
 No 227 90 (11) 68–112   Nr  
 received 52 33 (10) 14–52 0.0074 21 (4) 14–28 0.0003
               
Growth pattern
 Destructive 196 96 (13) 71–121   Nr  
 Papillary 38 48 (10) 28–68 0.1640 Nr 0.3039
 Alveolar 45 59 (25) 10–108 0.0130 22 (11) 0–44 0.0070
a

95% CI=95% confidence interval.

b

s.e.=standard error.

c

Not reached.